Cardiac Conduction Safety during Coadministration of Artemether-Lumefantrine and Lopinavir/Ritonavir in HIV-Infected Ugandan Adults

Background. We aimed to assess cardiac conduction safety of coadministration of the CYP3A4 inhibitor lopinavir/ritonavir (LPV/r) and the CYP3A4 substrate artemether-lumefantrine (AL) in HIV-positive Ugandans. Methods. Open-label safety study of HIV-positive adults administered single-dose AL (80/400...

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Autori principali: Byakika-Kibwika, Pauline, Lamorde, Mohammed, Lwabi, Peter, Nyakoojo, Wilson B., Okaba-Kayom, Violet, Mayanja-Kizza, Harriet, Boffito, Marta, Katabira, Elly, Back, David, Khoo, Saye, Merry, Concepta
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265243/
https://ncbi.nlm.nih.gov/pubmed/22312553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/393976
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