Pharmacokinetics of Telbivudine in Subjects with Various Degrees of Hepatic Impairment

This study evaluated the effect of hepatic impairment on the pharmacokinetics of telbivudine, an investigational nucleoside antiviral for the treatment of chronic hepatitis B virus infection. Twenty-four subjects were assigned to four hepatic function groups (normal function and mild, moderate, and...

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Detalhes bibliográficos
Main Authors: Zhou, Xiao-Jian, Marbury, Thomas C., Alcorn, Harry W., Smith, William B., Dubuc Patrick, Gloria, Chao, George C., Brown, Nathaniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472205/
https://ncbi.nlm.nih.gov/pubmed/16641441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1721-1726.2006
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