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Pharmacokinetics of Telbivudine in Subjects with Various Degrees of Hepatic Impairment

This study evaluated the effect of hepatic impairment on the pharmacokinetics of telbivudine, an investigational nucleoside antiviral for the treatment of chronic hepatitis B virus infection. Twenty-four subjects were assigned to four hepatic function groups (normal function and mild, moderate, and...

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書誌詳細
主要な著者: Zhou, Xiao-Jian, Marbury, Thomas C., Alcorn, Harry W., Smith, William B., Dubuc Patrick, Gloria, Chao, George C., Brown, Nathaniel A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472205/
https://ncbi.nlm.nih.gov/pubmed/16641441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1721-1726.2006
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