Pharmacokinetics of Telbivudine in Subjects with Various Degrees of Hepatic Impairment

This study evaluated the effect of hepatic impairment on the pharmacokinetics of telbivudine, an investigational nucleoside antiviral for the treatment of chronic hepatitis B virus infection. Twenty-four subjects were assigned to four hepatic function groups (normal function and mild, moderate, and...

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Bibliografiske detaljer
Main Authors: Zhou, Xiao-Jian, Marbury, Thomas C., Alcorn, Harry W., Smith, William B., Dubuc Patrick, Gloria, Chao, George C., Brown, Nathaniel A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472205/
https://ncbi.nlm.nih.gov/pubmed/16641441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1721-1726.2006
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