Pharmacokinetics of Telbivudine following Oral Administration of Escalating Single and Multiple Doses in Patients with Chronic Hepatitis B Virus Infection: Pharmacodynamic Implications

The pharmacokinetics of telbivudine were evaluated in adult patients with chronic hepatitis B virus (HBV) infection following once-daily oral administration at escalating doses of 25, 50, 100, 200, 400, and 800 mg/day for 4 weeks. Telbivudine was rapidly absorbed after oral administration, with the...

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Hlavní autoři: Zhou, Xiao-Jian, Lim, Seng-Gee, Lloyd, Deborah M., Chao, George C., Brown, Nathaniel A., Lai, Ching-Lung
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426427/
https://ncbi.nlm.nih.gov/pubmed/16495245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.874-879.2006
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