Caspase-11 protects against bacteria that escape the vacuole

Caspases are either apoptotic or inflammatory. The inflammatory Caspases-1 and -11 trigger pyroptosis, a form of programmed cell death. Whereas both can be detrimental in inflammatory disease, only Caspase-1 has an established protective role during infection. Herein, we report that Caspase-11 is re...

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Bibliografiske detaljer
Main Authors: Aachoui, Youssef, Leaf, Irina A., Hagar, Jon A., Fontana, Mary F., Campos, Cristine G., Zak, Daniel E., Tan, Michael H., Cotter, Peggy A., Vance, Russell E., Aderem, Alan, Miao, Edward A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697099/
https://ncbi.nlm.nih.gov/pubmed/23348507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1230751
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