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Detection of cytosolic bacteria by inflammatory caspases
The sanctity of the cytosolic compartment is rigorously maintained by a number of innate immune mechanisms. Inflammasomes detect signatures of microbial infection and trigger caspase-1 or caspase-11 activation, culminating in cytokine secretion and obliteration of the replicative niche via pyroptosi...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942666/ https://ncbi.nlm.nih.gov/pubmed/24581694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mib.2013.11.008 |
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