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Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
Either caspase-1 or caspase-11 can cleave gasdermin D to cause pyroptosis, eliminating intracellular replication niches. We previously showed that macrophages detect Burkholderia thailandensis via NLRC4, triggering the release of interleukin (IL)-18 and driving an essential interferon (IFN)-γ respon...
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| Foilsithe in: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7480168/ https://ncbi.nlm.nih.gov/pubmed/32726630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107967 |
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