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A Mutant Tat Protein Provides Strong Protection from HIV-1 Infection in Human CD4(+) T Cells

Here we show potent inhibition of HIV-1 replication in a human T cell line and primary human CD4(+) cells by expressing a single antiviral protein. Nullbasic is a mutant form of the HIV-1 Tat protein that was previously shown to strongly inhibit HIV-1 replication in nonhematopoietic cell lines by ta...

詳細記述

保存先:
書誌詳細
主要な著者: Apolloni, Ann, Lin, Min-Husan, Sivakumaran, Haran, Li, Dongsheng, Kershaw, Michael H.R., Harrich, David
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696950/
https://ncbi.nlm.nih.gov/pubmed/23298160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.176
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