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Overexpression of PRMT6 does not suppress HIV-1 Tat transactivation in cells naturally lacking PRMT6

BACKGROUND: Protein arginine methyltransferase 6 (PRMT6) can methylate the HIV-1 Tat, Rev and nucleocapsid proteins in a manner that diminishes each of their functions in in vitro assays, and increases the stability of Tat in human cells. In this study, we explored the relationship between PRMT6 and...

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Detalhes bibliográficos
Main Authors: Sivakumaran, Haran, Lin, Min-Hsuan, Apolloni, Ann, Cutillas, Vincent, Jin, Hongping, Li, Dongsheng, Wei, Ting, Harrich, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695826/
https://ncbi.nlm.nih.gov/pubmed/23800116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-207
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