Insights into β-Lactamases from Burkholderia Species, Two Phylogenetically Related yet Distinct Resistance Determinants

Burkholderia cepacia complex and Burkholderia pseudomallei are opportunistic human pathogens. Resistance to β-lactams among Burkholderia spp. is attributable to expression of β-lactamases (e.g. PenA in B. cepacia complex and PenI in B. pseudomallei). Phylogenetic comparisons reveal that PenA and Pen...

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Detalhes bibliográficos
Main Authors: Papp-Wallace, Krisztina M., Taracila, Magdalena A., Gatta, Julian A., Ohuchi, Nozomi, Bonomo, Robert A., Nukaga, Michiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696682/
https://ncbi.nlm.nih.gov/pubmed/23658015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458315
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