Exploring the Role of the Ω-Loop in the Evolution of Ceftazidime Resistance in the PenA β-Lactamase from Burkholderia multivorans, an Important Cystic Fibrosis Pathogen

The unwelcome evolution of resistance to the advanced generation cephalosporin antibiotic, ceftazidime is hindering the effective therapy of Burkholderia cepacia complex (BCC) infections. Regrettably, BCC organisms are highly resistant to most antibiotics, including polymyxins; ceftazidime and trime...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Papp-Wallace, Krisztina M., Becka, Scott A., Taracila, Magdalena A., Zeiser, Elise T., Gatta, Julian A., LiPuma, John J., Bonomo, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Mechanisms of Resistance
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278747/
https://ncbi.nlm.nih.gov/pubmed/27872073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01941-16
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items