Assessing the Potency of β-Lactamase Inhibitors with Diverse Inactivation Mechanisms against the PenA1 Carbapenemase from Burkholderia multivorans

Burkholderia cepacia complex (Bcc) poses a serious health threat to people with cystic fibrosis or compromised immune systems. Infections often arise from Bcc strains, which are highly resistant to many classes of antibiotics, including β-lactams. β-Lactam resistance in Bcc is conferred largely via...

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Udgivet i:ACS Infect Dis
Main Authors: Nukaga, Michiyoshi, Yoon, Michael J., Taracilia, Magdalena A., Hoshino, Tyuji, Becka, Scott A., Zeiser, Elise T., Johnson, Joseph R., Papp-Wallace, Krisztina M.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324038/
https://ncbi.nlm.nih.gov/pubmed/33723985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00682
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