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Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1

BACKGROUND AND PURPOSE: Shikonin was reported to induce necroptosis in leukemia cells, but apoptosis in glioma cell lines. Thus, it is needed to clarify whether shikonin could cause necroptosis in glioma cells and investigate its underlying mechanisms. METHODS: Shikonin and rat C6 glioma cell line a...

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Hlavní autoři: Huang, Chuanjiang, Luo, Yinan, Zhao, Jingwei, Yang, Fuwei, Zhao, Hongwei, Fan, Wenhai, Ge, Pengfei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695975/
https://ncbi.nlm.nih.gov/pubmed/23840441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066326
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