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Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis
BACKGROUND: Necroptotic susceptibility is probably an intrinsic weakness of cancer. Here, we report that resibufogenin, a member of bufadienolide family, suppresses the growth and metastasis of colorectal cancer (CRC) through induction of necroptosis in vivo. METHODS: SW480 cells with stably express...
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| Publicado no: | J Transl Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6053767/ https://ncbi.nlm.nih.gov/pubmed/30029665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1580-x |
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