Ppm1b negatively regulates necroptosis through dephosphorylating Rip3

The auto-phosphorylation of murine receptor-interacting protein 3 (Rip3) on Thr 231 and Ser 232 in the necrosome is required to trigger necroptosis. However, how Rip3 phosphorylation is regulated is still largely unknown. Here we identified protein phosphatase 1B (Ppm1b) as a Rip3 phosphatase and fo...

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Detaylı Bibliyografya
Yayımlandı:Nat Cell Biol
Asıl Yazarlar: Chen, Wanze, Wu, Jianfeng, Li, Lisheng, Zhang, Zhengmao, Ren, Junming, Liang, Yaoji, Chen, Fenfang, Yang, Chao, Zhou, Zhenru, Su, Sheng Sean, Zheng, Xinru, Zhang, Zhirong, Zhong, Chuan-Qi, Wan, Haoqiang, Xiao, Mu, Lin, Xia, Feng, Xin-Hua, Han, Jiahuai
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523090/
https://ncbi.nlm.nih.gov/pubmed/25751141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3120
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