The Gβγ-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation

Formation of multi-component signaling complex necrosomes is essential for tumor necrosis factor α (TNF)-induced programmed necrosis (also called necroptosis). However, the mechanisms of necroptosis are still largely unknown. We isolated a TNF-resistant L929 mutant cell line generated by retrovirus...

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Main Authors: Li, Lisheng, Chen, Wanze, Liang, Yaoji, Ma, Huabin, Li, Wenjuan, Zhou, Zhenru, Li, Jie, Ding, Yan, Ren, Junming, Lin, Juan, Han, Felicia, Wu, Jianfeng, Han, Jiahuai
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975499/
https://ncbi.nlm.nih.gov/pubmed/24513853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.17
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