Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA

BACKGROUND: The K65R substitution in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) is the major resistance mutation selected in patients treated with first-line antiretroviral tenofovir disoproxil fumarate (TDF). 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA), is the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Michailidis, Eleftherios, Ryan, Emily M, Hachiya, Atsuko, Kirby, Karen A, Marchand, Bruno, Leslie, Maxwell D, Huber, Andrew D, Ong, Yee T, Jackson, Jacob C, Singh, Kamalendra, Kodama, Eiichi N, Mitsuya, Hiroaki, Parniak, Michael A, Sarafianos, Stefan G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695782/
https://ncbi.nlm.nih.gov/pubmed/23800377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-65
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia