Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system

The universally conserved Kae1/Qri7/YgjD and Sua5/YrdC protein families have been implicated in growth, telomere homeostasis, transcription and the N6-threonylcarbamoylation (t(6)A) of tRNA, an essential modification required for translational fidelity by the ribosome. In bacteria, YgjD orthologues...

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Detalhes bibliográficos
Main Authors: Wan, Leo C. K., Mao, Daniel Y. L., Neculai, Dante, Strecker, Jonathan, Chiovitti, David, Kurinov, Igor, Poda, Gennadiy, Thevakumaran, Neroshan, Yuan, Fang, Szilard, Rachel K., Lissina, Elena, Nislow, Corey, Caudy, Amy A., Durocher, Daniel, Sicheri, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695523/
https://ncbi.nlm.nih.gov/pubmed/23620299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt322
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