Reconstitution and characterization of eukaryotic N6-threonylcarbamoylation of tRNA using a minimal enzyme system

The universally conserved Kae1/Qri7/YgjD and Sua5/YrdC protein families have been implicated in growth, telomere homeostasis, transcription and the N6-threonylcarbamoylation (t(6)A) of tRNA, an essential modification required for translational fidelity by the ribosome. In bacteria, YgjD orthologues...

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Bibliografiske detaljer
Main Authors: Wan, Leo C. K., Mao, Daniel Y. L., Neculai, Dante, Strecker, Jonathan, Chiovitti, David, Kurinov, Igor, Poda, Gennadiy, Thevakumaran, Neroshan, Yuan, Fang, Szilard, Rachel K., Lissina, Elena, Nislow, Corey, Caudy, Amy A., Durocher, Daniel, Sicheri, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695523/
https://ncbi.nlm.nih.gov/pubmed/23620299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt322
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