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Focus on Histone variant H2AX: to be or not to be
Phosphorylation of histone variant H2AX at serine 139, named γH2AX, has been widely used as a sensitive marker for DNA double-strand breaks (DSBs). γH2AX is required for the accumulation of many DNA damage response (DDR) proteins at DSBs. Thus it is believed to be the principal signaling protein inv...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3695482/ https://ncbi.nlm.nih.gov/pubmed/20493860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.05.021 |
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