Critical Role of Monoubiquitination of Histone H2AX Protein in Histone H2AX Phosphorylation and DNA Damage Response

DNA damage response is an important surveillance mechanism used to maintain the integrity of the human genome in response to genotoxic stress. Histone variant H2AX is a critical sensor that undergoes phosphorylation at serine 139 upon genotoxic stress, which provides a docking site to recruit the me...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wu, Ching-Yuan, Kang, Hong-Yo, Yang, Wei-Lei, Wu, Juan, Jeong, Yun Seong, Wang, Jing, Chan, Chia-Hsin, Lee, Szu-Wei, Zhang, Xian, Lamothe, Betty, Campos, Alejandro D., Darnay, Bryant G., Lin, Hui-Kuan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162441/
https://ncbi.nlm.nih.gov/pubmed/21690091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.257469
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky