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ADP‐ribosylation of histone variant H2AX promotes base excision repair
Optimal DNA damage response is associated with ADP‐ribosylation of histones. However, the underlying molecular mechanism of DNA damage‐induced histone ADP‐ribosylation remains elusive. Herein, using unbiased mass spectrometry, we identify that glutamate residue 141 (E141) of variant histone H2AX is...
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| Опубликовано в: : | EMBO J |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809701/ https://ncbi.nlm.nih.gov/pubmed/33264433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104542 |
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