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The role of poly ADP-ribosylation in the first wave of DNA damage response
Poly ADP-ribose polymerases (PARPs) catalyze massive protein poly ADP-ribosylation (PARylation) within seconds after the induction of DNA single- or double-strand breaks. PARylation occurs at or near the sites of DNA damage and promotes the recruitment of DNA repair factors via their poly ADP-ribose...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737498/ https://ncbi.nlm.nih.gov/pubmed/28854736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx565 |
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