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The Role of Poly(ADP-ribosyl)ation in DNA Damage Response and Cancer Chemotherapy

DNA damage is a deleterious threat, but occurs daily in all types of cells. In response to DNA damage, poly(ADP-ribosyl)ation, a unique posttranslational modification, is immediately catalyzed by poly(ADP-ribose) polymerases (PARPs) at DNA lesions, which facilitates DNA damage repair. Recent studies...

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Bibliografiska uppgifter
I publikationen:Oncogene
Huvudupphovsmän: Li, Mo, Yu, Xiaochun
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362780/
https://ncbi.nlm.nih.gov/pubmed/25220415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.295
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