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The Role of Poly(ADP-ribosyl)ation in DNA Damage Response and Cancer Chemotherapy
DNA damage is a deleterious threat, but occurs daily in all types of cells. In response to DNA damage, poly(ADP-ribosyl)ation, a unique posttranslational modification, is immediately catalyzed by poly(ADP-ribose) polymerases (PARPs) at DNA lesions, which facilitates DNA damage repair. Recent studies...
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| Publicado no: | Oncogene |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362780/ https://ncbi.nlm.nih.gov/pubmed/25220415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.295 |
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