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Poly-ADP ribosylation in DNA damage response and cancer therapy
Poly(ADP-ribosyl)ation (aka PARylation) is a unique protein post-translational modification (PTM) first described over 50 years ago. PARylation regulates a number of biological processes including chromatin remodeling, the DNA damage response (DDR), transcription, apoptosis, and mitosis. The subsequ...
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| Publicado en: | Mutat Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690395/ https://ncbi.nlm.nih.gov/pubmed/31395352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2017.09.004 |
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