The histone variant H2A.X is a regulator of the epithelial–mesenchymal transition

The epithelial–mesenchymal transition (EMT), considered essential for metastatic cancer, has been a focus of much research, but important questions remain. Here, we show that silencing or removing H2A.X, a histone H2A variant involved in cellular DNA repair and robust growth, induces mesenchymal-lik...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Weyemi, Urbain, Redon, Christophe E., Choudhuri, Rohini, Aziz, Towqir, Maeda, Daisuke, Boufraqech, Myriem, Parekh, Palak R., Sethi, Taresh K., Kasoji, Manjula, Abrams, Natalie, Merchant, Anand, Rajapakse, Vinodh N., Bonner, William M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756313/
https://ncbi.nlm.nih.gov/pubmed/26876487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10711
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