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PUMA: A Unified Framework for Penalized Multiple Regression Analysis of GWAS Data

Penalized Multiple Regression (PMR) can be used to discover novel disease associations in GWAS datasets. In practice, proposed PMR methods have not been able to identify well-supported associations in GWAS that are undetectable by standard association tests and thus these methods are not widely appl...

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Détails bibliographiques
Auteurs principaux: Hoffman, Gabriel E., Logsdon, Benjamin A., Mezey, Jason G.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694815/
https://ncbi.nlm.nih.gov/pubmed/23825936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003101
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