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A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis

BACKGROUND: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to explain the bulk of heritability. Here, we describe the algorithm V-Bay, a variational Bayes algorithm for multiple locus GWA...

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Detalhes bibliográficos
Main Authors: Logsdon, Benjamin A, Hoffman, Gabriel E, Mezey, Jason G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824680/
https://ncbi.nlm.nih.gov/pubmed/20105321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-58
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