STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis

The STAT3 transcription factor is an important regulator of stem cell self-renewal, cancer cell survival, and inflammation. In the pancreas, STAT3 is dispensable for normal development whereas the majority of pancreatic ductal adenocarcinomas (PDAC) show constitutive activation of STAT3, suggesting...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Corcoran, Ryan B., Contino, Gianmarco, Deshpande, Vikram, Tzatsos, Alexandros, Conrad, Claudius, Benes, Cyril H., Settleman, Jeffrey, Engelman, Jeffrey A., Bardeesy, Nabeel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693754/
https://ncbi.nlm.nih.gov/pubmed/21586612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0908
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg