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Modeling catalytic promiscuity in the alkaline phosphatase superfamily

In recent years, it has become increasingly clear that promiscuity plays a key role in the evolution of new enzyme function. This finding has helped to elucidate fundamental aspects of molecular evolution. While there has been extensive experimental work on enzyme promiscuity, computational modeling...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duarte, Fernanda, Amrein, Beat Anton, Kamerlin, Shina Caroline Lynn
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693508/
https://ncbi.nlm.nih.gov/pubmed/23728154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cp51179k
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