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Modeling catalytic promiscuity in the alkaline phosphatase superfamily

In recent years, it has become increasingly clear that promiscuity plays a key role in the evolution of new enzyme function. This finding has helped to elucidate fundamental aspects of molecular evolution. While there has been extensive experimental work on enzyme promiscuity, computational modeling...

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Bibliografische gegevens
Hoofdauteurs: Duarte, Fernanda, Amrein, Beat Anton, Kamerlin, Shina Caroline Lynn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Royal Society of Chemistry 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693508/
https://ncbi.nlm.nih.gov/pubmed/23728154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cp51179k
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