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Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily

The nucleotide phosphodiesterase/pyrophosphatase from Xanthomonas axonopodis (NPP) is a structural and evolutionary relative of alkaline phosphatase that preferentially hydrolyzes phosphate diesters. With the goal of understanding how these two enzymes with nearly identical Zn(2+) bimetallo sites ac...

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Detalhes bibliográficos
Main Authors: Lassila, Jonathan K., Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662379/
https://ncbi.nlm.nih.gov/pubmed/18975918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801488c
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