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Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily
The nucleotide phosphodiesterase/pyrophosphatase from Xanthomonas axonopodis (NPP) is a structural and evolutionary relative of alkaline phosphatase that preferentially hydrolyzes phosphate diesters. With the goal of understanding how these two enzymes with nearly identical Zn(2+) bimetallo sites ac...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662379/ https://ncbi.nlm.nih.gov/pubmed/18975918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801488c |
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