HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells

We revealed the cytotoxic effect of the flavonoid, fisetin (FIS), on human COLO205 colon cancer cells in the presence and absence of the HSP90 inhibitors, geldanamycin (GA) and radicicol (RAD). Compared to FIS treatment alone of COLO205 cells, GA and RAD significantly enhanced FIS-induced cytotoxici...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wu, Ming-Shun, Lien, Gi-Shih, Shen, Shing-Chuan, Yang, Liang-Yo, Chen, Yen-Chou
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693119/
https://ncbi.nlm.nih.gov/pubmed/23840275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/987612
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados