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Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

Fragile X syndrome is the most common inherited form of cognitive deficiency in humans and perhaps the best-understood single cause of autism. A trinucleotide repeat expansion, inactivating the X-linked FMR1 gene, leads to the absence of the fragile X mental retardation protein. FMRP is a selective...

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Autori principali: Bassell, Gary J., Warren, Stephen T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3691995/
https://ncbi.nlm.nih.gov/pubmed/18957214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.10.004
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