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Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function
Fragile X syndrome is the most common inherited form of cognitive deficiency in humans and perhaps the best-understood single cause of autism. A trinucleotide repeat expansion, inactivating the X-linked FMR1 gene, leads to the absence of the fragile X mental retardation protein. FMRP is a selective...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3691995/ https://ncbi.nlm.nih.gov/pubmed/18957214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.10.004 |
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