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Membrane phospholipid bilayer as a determinant of monoacylglycerol lipase kinetic profile and conformational repertoire
The membrane-associated serine hydrolase, monoacylglycerol lipase (MGL), is a well-recognized therapeutic target that regulates endocannabinoid signaling. Crystallographic studies, while providing structural information about static MGL states, offer no direct experimental insight into the impact of...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690717/ https://ncbi.nlm.nih.gov/pubmed/23553709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2257 |
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