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Endocannabinoid Enzyme Engineering: Soluble Human Thio-Monoacylglycerol Lipase (sol-S-hMGL)
[Image: see text] In the mammalian central nervous system, monoacylglycerol lipase (MGL) is principally responsible for inactivating the endocannabinoid signaling lipid 2-arachidonoylglycerol (2-AG) and modulates cannabinoid-1 receptor (CB1R) desensitization and signal intensity. MGL is also a drug...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical
Society
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3400385/ https://ncbi.nlm.nih.gov/pubmed/22860208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3000263 |
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