Membrane phospholipid bilayer as a determinant of monoacylglycerol lipase kinetic profile and conformational repertoire

The membrane-associated serine hydrolase, monoacylglycerol lipase (MGL), is a well-recognized therapeutic target that regulates endocannabinoid signaling. Crystallographic studies, while providing structural information about static MGL states, offer no direct experimental insight into the impact of...

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Detaylı Bibliyografya
Asıl Yazarlar: Nasr, Mahmoud L, Shi, Xiaomeng, Bowman, Anna L, Johnson, Michael, Zvonok, Nikolai, Janero, David R, Vemuri, V Kiran, Wales, Thomas E, Engen, John R, Makriyannis, Alexandros
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2013
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690717/
https://ncbi.nlm.nih.gov/pubmed/23553709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2257
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