Expression of αV-Integrins in Uterine Serous Papillary Carcinomas; Implications for Targeted Therapy With Intetumumab (CNTO 95), a Fully Human Antagonist Anti–αV-Integrin Antibody

OBJECTIVE: Uterine serous papillary carcinoma (USPC) is an aggressive variant of endometrial cancer characterized by an innate resistance to chemotherapy and poor prognosis. In this study, we evaluated the expression of αV-integrins in primary USPC cell lines and the in vitro ability of intetumumab...

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Autors principals: Bellone, Marta, Cocco, Emiliano, Varughese, Joyce, Bellone, Stefania, Todeschini, Paola, El-Sahwi, Karim, Carrara, Luisa, Guzzo, Federica, Schwartz, Peter E., Rutherford, Thomas J., Pecorelli, Sergio, Marshall, Deborah J., Santin, Alessandro D.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690508/
https://ncbi.nlm.nih.gov/pubmed/21633302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/IGC.0b013e3182187324
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