In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma

BACKGROUND: Uterine serous papillary adenocarcinoma (USPC) is a rare but highly aggressive variant of endometrial cancer. Pertuzumab is a new humanised monoclonal antibody (mAb) targeting the epidermal growth factor type II receptor (HER2/neu). We evaluated pertuzumab activity separately or in combi...

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Bibliographic Details
Main Authors: El-Sahwi, K, Bellone, S, Cocco, E, Cargnelutti, M, Casagrande, F, Bellone, M, Abu-Khalaf, M, Buza, N, Tavassoli, F A, Hui, P, Silasi, D-A, Azodi, M, Schwartz, P E, Rutherford, T J, Pecorelli, S, Santin, A D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
Subjects:
Translational Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813756/
https://ncbi.nlm.nih.gov/pubmed/19920829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605448
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