HER2/neu as a potential target for immunotherapy in gynecological carcinosarcomas

Carcinosarcomas of the female genital tract are rare tumors with aggressive clinical behavior. Trastuzumab, a humanized monoclonal antibody, acts by binding to HER2/neu extracellular domain and exhibits therapeutic efficacy in HER2/neu over-expressing cancers. Two uterine carcinosarcomas (UMMT-ARK-1...

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Detalhes bibliográficos
Main Authors: Guzzo, Federica, Bellone, Stefania, Buza, Natalia, Hui, Pei, Carrara, Luisa, Varughese, Joyce, Cocco, Emiliano, Betti, Marta, Todeschini, Paola, Gasparrini, Sara, Schwartz, Peter E., Rutherford, Thomas J., Angioli, Roberto, Pecorelli, Sergio, Santin, Alessandro D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366047/
https://ncbi.nlm.nih.gov/pubmed/22498937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PGP.0b013e31823bb24d
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