Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti-Trop-2 antibody

BACKGROUND: We evaluated the expression of human trophoblastic cell-surface marker (Trop-2) and the potential of hRS7 - a humanized monoclonal anti-Trop-2 antibody - as a therapeutic strategy against treatment-refractory human uterine (UMMT) and ovarian (OMMT) carcinosarcoma cell lines. MATERIALS AN...

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Detalhes bibliográficos
Main Authors: Raji, Rhoda, Guzzo, Federica, Carrara, Luisa, Varughese, Joyce, Cocco, Emiliano, Bellone, Stefania, Betti, Marta, Todeschini, Paola, Gasparrini, Sara, Ratner, Elena, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter, Rutherford, Thomas J, Buza, Natalia, Pecorelli, Sergio, Santin, Alessandro D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224774/
https://ncbi.nlm.nih.gov/pubmed/22075385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-106
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