Cervical carcinomas overexpress human trophoblast cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized monoclonal anti-Trop-2 antibody

OBJECTIVES: We evaluated the expression of human-trophoblast-cell-surface-marker (Trop-2) and the potential of hRS7, a humanized-monoclonal-anti-Trop-2-antibody, against treatment-refractory cervical cancer. STUDY DESIGN: Trop-2 expression was evaluated by immunohistochemistry (IHC), real-time polym...

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Autori principali: Varughese, Joyce, Cocco, Emiliano, Bellone, Stefania, Ratner, Elena, Silasi, Dan-Arin, Azodi, Masoud, Schwartz, Peter E., Rutherford, Thomas J., Buza, Natalia, Pecorelli, Sergio, Santin, Alessandro D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3224189/
https://ncbi.nlm.nih.gov/pubmed/21889762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2011.06.093
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