Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium tuberculosis Pantothenate Kinase

Mycobacterium tuberculosis, the bacterial causative agent of tuberculosis, currently affects millions of people. The emergence of drug-resistant strains makes development of new antibiotics targeting the bacterium a global health priority. Pantothenate kinase, a key enzyme in the universal biosynthe...

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Main Authors: Björkelid, Christofer, Bergfors, Terese, Raichurkar, Anand Kumar V., Mukherjee, Kakoli, Malolanarasimhan, Krishnan, Bandodkar, Balachandra, Jones, T. Alwyn
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689968/
https://ncbi.nlm.nih.gov/pubmed/23661699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.476473
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