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Structural and Biochemical Analyses of Mycobacterium tuberculosis N-Acetylmuramyl-l-alanine Amidase Rv3717 Point to a Role in Peptidoglycan Fragment Recycling

Peptidoglycan hydrolases are key enzymes in bacterial cell wall homeostasis. Understanding the substrate specificity and biochemical activity of peptidoglycan hydrolases in Mycobacterium tuberculosis is of special interest as it can aid in the development of new cell wall targeting therapeutics. In...

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Autors principals: Prigozhin, Daniil M., Mavrici, Daniela, Huizar, John P., Vansell, Hilary J., Alber, Tom
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814751/
https://ncbi.nlm.nih.gov/pubmed/24019530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.510792
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