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Absence of Pharmacokinetic and Pharmacodynamic Interactions between Almorexant and Warfarin in Healthy Subjects

BACKGROUND AND OBJECTIVE: Almorexant is the first representative of the new class of orexin receptor antagonists, which could become a new treatment option for insomnia. The present study investigated the potential interaction between almorexant and warfarin. METHODS: In this open-label, two-way cro...

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Bibliographic Details
Main Authors: Dingemanse, Jasper, Hoever, Petra
Format: Artigo
Language:Inglês
Published: Springer International Publishing AG 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689907/
https://ncbi.nlm.nih.gov/pubmed/23737453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-013-0017-5
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