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Pharmacokinetic and pharmacodynamic interaction between ezetimibe and rosuvastatin in healthy male subjects

BACKGROUND AND OBJECTIVE: Rosuvastatin and ezetimibe are commonly applied in lipid-lowering pharmacotherapy. However, the pharmacokinetic (PK) interaction was not clear by the coadministration of rosuvastatin and ezetimibe. This study investigated the pharmacodynamic (PD) and PK interactions between...

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Foilsithe in:Drug Des Devel Ther
Main Authors: Kim, Chang Hee, An, Hyungmi, Kim, Sung Hye, Shin, Dongseong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5723108/
https://ncbi.nlm.nih.gov/pubmed/29255347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S146863
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