Pharmacokinetic interactions and tolerability of rosuvastatin and ezetimibe: an open-label, randomized, multiple-dose, crossover study in healthy male volunteers

PURPOSE: Rosuvastatin is a synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor that effectively reduces low-density lipoprotein cholesterol levels. However, statin monotherapy does not always achieve acceptable low-density lipoprotein cholesterol levels in patients with severe hyperc...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Kim, Hyungsub, Choi, Hee Youn, Kim, Yo-Han, Bae, Kyun-Seop, Jung, Jina, Son, Hankil, Lim, Hyeong-Seok
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903480/
https://ncbi.nlm.nih.gov/pubmed/29692602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S158408
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