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Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers

BACKGROUND: HX-1171 (1-O-hexyl-2,3,5-trimethylhydroquinone) is a promising antioxidant with therapeutic potential for hepatic fibrosis. The aim of this study was to investigate the tolerability and pharmacokinetics of HX-1171 in healthy volunteers. METHODS: A randomized, single-blind, placebo-contro...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Kim, Yo Han, Choi, Hee Youn, Lee, Shi Hyang, Lim, Hyeong-Seok, Miki, Tokutaro, Kang, Jong-Koo, Han, Kyoung-Goo, Bae, Kyun-Seop
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376184/
https://ncbi.nlm.nih.gov/pubmed/25848210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S79724
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