Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

BACKGROUND: Donepezil is an acetylcholinesterase inhibitor indicated for Alzheimer’s disease. The aim of this randomized, single-blind, placebo-controlled, single-dose, dose-escalation study was to investigate the safety, tolerability, and pharmacokinetics of the donepezil patch in healthy male subj...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Kim, Yo Han, Choi, Hee Youn, Lim, Hyeong-Seok, Lee, Shi Hyang, Jeon, Hae Sun, Hong, Donghyun, Kim, Seong Su, Choi, Young Kweon, Bae, Kyun-Seop
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362658/
https://ncbi.nlm.nih.gov/pubmed/25792802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S78555
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