Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects

AIMS: This study investigated the pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects. METHODS: This was an open-label, randomized, three-treatment, cross-over, clinical trial in healthy male subjects (n= 12) of known CYP2C9 and VKORC1 geno...

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Detalhes bibliográficos
Main Authors: Abdul, Mohi Iqbal Mohammed, Jiang, Xuemin, Williams, Kenneth M, Day, Richard O, Roufogalis, Basil D, Liauw, Winston S, Xu, Hongmei, Matthias, Anita, Lehmann, Reginald P, McLachlan, Andrew J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Drug Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856051/
https://ncbi.nlm.nih.gov/pubmed/20573086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03620.x
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