Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide

BACKGROUND AND PURPOSE: Patients commonly take complementary medicines in conjunction with conventional drugs without clear evidence of safety or the risk of herb–drug interactions. The aim of this study was to assess potential pharmacokinetic (PK) and pharmacodynamic (PD) interactions between St Jo...

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Detalhes bibliográficos
Main Authors: Xu, H, Williams, K M, Liauw, W S, Murray, M, Day, R O, McLachlan, A J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2437900/
https://ncbi.nlm.nih.gov/pubmed/18204476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707685
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